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Updated: Jun 2, 2025

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Analysis of Urinary Metanephrines Using Liquid Chromatography Tandem Mass Spectrometry

Marlene N Thaitumu1,2, Elizabeth L Frank3

  • 1Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA.

Methods in Molecular Biology (Clifton, N.J.)
|January 15, 2025
PubMed
Summary

This study presents an optimized liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for measuring urinary metanephrines. This method enhances the sensitive and specific screening of pheochromocytoma, a neuroendocrine tumor.

Keywords:
Liquid chromatography-tandem mass spectrometryMetanephrinesPheochromocytoma

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