Related Experiment Video

Updated: Jun 2, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.3K

Gastrointestinal bleed mortality disparities in patients with atrial fibrillation: A cross-sectional analysis

Enkhtsogt Sainbayar1, Ramzi Ibrahim2, Sangkyu Noh1

  • 1Department of Medicine University of Arizona Tucson Tucson Arizona USA.

Journal of Arrhythmia
|January 16, 2025
PubMed

Insights

Gastrointestinal bleeding deaths in patients with atrial fibrillation (AF) increased significantly from 1999-2020, with higher rates in males, White populations, and rural areas. Targeted interventions are needed for these vulnerable groups.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Public Health

Background:

  • Gastrointestinal bleeding (GIB) is a significant concern for patients with atrial fibrillation (AF) due to anticoagulation therapy.
  • Understanding disparities in GIB-related mortality is crucial for effective public health strategies.

Purpose of the Study:

  • To assess trends and disparities in gastrointestinal bleeding (GIB)-related mortality among decedents with atrial fibrillation (AF) in the United States.
  • To identify demographic and geographic factors associated with increased GIB mortality in the AF population.

Main Methods:

  • Utilized CDC WONDER database for GIB mortality data in AF patients (1999-2020).
  • Analyzed decedent demographic information from death certificates, including age, sex, race, ethnicity, and residence.
  • Calculated age-adjusted mortality rates (AAMRs) and estimated annual percentage change (APC) using log-linear regression.

Main Results:

  • Overall GIB mortality in AF decedents rose from 0.12 in 1999 to 0.21 in 2020 (APC +4.8% from 2009-2020).
  • Higher mortality rates were observed in males, White populations, and individuals residing in rural areas compared to females, Black populations, and urban areas.
  • Mortality increased significantly in urban regions after 2009 (APC +4.83%) and consistently in rural regions (APC +4.08%). The Northeast US had the highest mortality rate.

Conclusions:

  • Significant disparities in GIB mortality exist among AF decedents in the US.
  • Findings highlight the urgent need for targeted interventions to reduce GIB risks in vulnerable patient subgroups.
  • Further research into the specific drivers of these disparities is warranted to inform clinical practice and public health policy.
Abstract

Keywords:
arrhythmiaatrial fibrillationgastrointestinalhemorrhage

More Related Videos

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.4K
Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

11.6K

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
46
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
694