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Manufacture and Drug Delivery Applications of Silk Nanoparticles
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Advanced Drug Delivery Systems: From Microsponges to Nanotechnologies

Stefano Fiorucci1, Ginevra Urbani1

  • 1Department of Medicine and Surgery University of Perugia, Perugia, Italy.

Recent Advances in Inflammation & Allergy Drug Discovery
|January 17, 2025
PubMed
Abstract

No abstract available in PubMed .

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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