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Updated: Jun 2, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Designing an intervention to improve cognitive evaluations in primary care.
Kyra S O'Brien1,2, Kristin Harkins3, MaryAnne Peifer4
1Department of Neurology, University of Pennsylvania Perelman School of Medicine, 3400 Spruce Street, 3W Gates, Philadelphia, PA, 19104, USA. kyra.o'brien@pennmedicine.upenn.edu.
Early diagnosis of cognitive impairment is vital. This study identified barriers and facilitators to cognitive evaluations in primary care, leading to six promising strategies for improved dementia diagnosis.
Area of Science:
- Gerontology
- Primary Care Medicine
- Neuroscience
Background:
- Early diagnosis of Alzheimer's disease (AD) and related dementias is critical for patient management and access to therapies.
- Primary care providers (PCPs) often underdiagnose cognitive impairment, with significant variability in evaluation methods.
- Understanding barriers and facilitators is key to improving dementia diagnosis in primary care settings.
Purpose of the Study:
- To identify barriers and facilitators to cognitive evaluations in primary care.
- To map these barriers to implementation strategies.
- To reach consensus on strategies for improving dementia diagnosis in primary care.
Main Methods:
- Semi-structured interviews with 20 primary care providers (PCPs).
- Used Consolidated Framework for Implementation Research and chart-stimulated recall.
- Expert stakeholder panel utilized a modified Delphi process to narrow down strategies.
Main Results:
- Key barriers included lack of expertise, time pressures, and limited specialist access.
- Facilitators involved caregiver presence and additional staff for testing.
- 15 candidate strategies were narrowed to six promising interventions.
Conclusions:
- A rigorous process identified key barriers, facilitators, and promising implementation strategies for cognitive assessments.
- This work provides a foundation for future trials to improve primary care dementia diagnosis.
- Stakeholder consensus was achieved on strategies to enhance cognitive evaluations.
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