Optimizing the hyperbaric chamber pressurization profile during standard hyperbaric oxygen therapy

Middle ear barotrauma (MEBT) is the most common complication in providing hyperbaric oxygen therapy (HBO₂). This study explored the impact of altering the shape of the time-pressure curve with the aim of reducing the occurrence of MEBT and optimizing the HBO₂ experience during the pressurization process. Four distinct mathematically derived protocols-Constant Pressure Difference (CPD), Constant Volume Difference (CVD), Constant Ratio (CR), and Inverted Constant Ratio (ICR)-were investigated using computer simulations on a simple ear model. Results indicated varying levels of ear strain during pressurization. The CR pressurization demonstrated balanced ear strain levels and outperformed other modalities in several measures, including the impact on the simulated ear cavity volume. The potential for enhanced patient comfort through the application of sophisticated pressurization protocols warrants further research to validate and extend the findings of this study in real-world HBO₂ settings.