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Updated: Jun 23, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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A Retrospective Review of Oral N-Acetylcysteine for Habit-Driven Cutaneous Disorders
Diana H Zarowin1,2, Amy Buros Stein3, Sarah E Sheppard4
1Albert Einstein College of Medicine, Bronx, New York, USA.
Abstract:
Oral N-acetylcysteine (NAC) has shown efficacy for debilitating habit-driven and neuropsychiatric disorders in small, mostly adult studies. We retrospectively evaluated the therapeutic use and safety of oral NAC in 93 children from the Children's Hospital of Philadelphia. This study supports the use of oral NAC for habit-driven skin, hair, and nail abnormalities in pediatric patients.
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