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Updated: Jun 1, 2025

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Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
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A Case of Merkel Cell Carcinoma of Unknown Primary Origin Presenting With High Merkel Cell Polyomavirus DNA Levels in
Issei Kido1, Takao Kadono1, Yumiko Hashida2
1Dermatology, Kochi University, Nankoku, JPN.
Cureus
|January 17, 2025
Abstract:
Merkel cell carcinoma is a rare neuroendocrine tumor with high mortality. It is well known that clonal integration of the Merkel cell polyomavirus into the dermal precursor cells is a hypothesized pathway in Merkel cell carcinoma pathogenesis. Here, we demonstrate a case of Merkel cell carcinoma (primary origin unknown) presenting with high Merkel cell polyomavirus DNA levels in swabs obtained from normal skin.
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