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Resistance Training and the Risk of Breast Cancer: A Population-Based Case-Control Study
Hiya Deepak Modi1, Stephanie Byrne1,2,3, L S Katrina Li4,5
1Australian Center for Precision Health, Allied Health & Human Performance, University of South Australia, Adelaide, SA, Australia.
Journal of Physical Activity & Health
|January 18, 2025
Summary
Resistance training (RT) in early adulthood was linked to a 52% reduced breast cancer risk. However, RT in later life or overall lifetime RT showed no association with breast cancer prevention.
Area of Science:
- Oncology
- Epidemiology
- Exercise Science
Background:
- Moderate to vigorous physical activity is known to reduce breast cancer risk.
- The specific impact of resistance training (RT) on breast cancer prevention requires further investigation.
Purpose of the Study:
- To investigate the association between resistance training (RT) and breast cancer risk.
- To explore if RT during different life stages influences breast cancer risk.
Main Methods:
- A population-based case-control study involving 1149 cases and 1710 controls aged 18-80 years in Western Australia.
- Participants retrospectively reported recreational physical activities, including RT, across three age periods: 15-24, 25-39, and 40+ years.
- Logistic regression analysis was employed to assess the relationship between RT and breast cancer risk, adjusting for potential confounders.
Main Results:
- Engaging in RT between ages 15-24 was associated with a 52% lower risk of breast cancer compared to no RT.
- No significant association was found between RT during the 25-39 or 40+ age periods and breast cancer risk.
- Lifetime RT also did not show a statistically significant association with reduced breast cancer risk.
Conclusions:
- Resistance training during early adulthood (15-24 years) may play a role in lowering breast cancer risk.
- RT in later adulthood or overall lifetime RT did not demonstrate a protective effect against breast cancer in this study.
- Further research is needed to confirm these preliminary findings and explore the nuances of RT's impact on breast cancer prevention across the lifespan.
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