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An International Delphi-Based Study for Developing a Core Outcome Set for Hypospadias Surgery.

Tina L Leunbach1,2, Francisca Yankovic3,4, Alexander Springer5

  • 1Department of Urology, Section of Paediatric Urology, Aarhus University Hospital, Aarhus, Denmark.

Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
|January 19, 2025
PubMed
Summary
This summary is machine-generated.

Establishing a core outcome set (COS) for hypospadias surgery harmonizes reporting. Core outcomes for younger boys were consistent, but varied for older boys, indicating less clarity.

Keywords:
Delphi studyHypospadiasLong-term adverse effectsRe-operationTreatment outcome

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Area of Science:

  • Pediatric Urology
  • Surgical Outcomes Research
  • Core Outcome Set Development

Background:

  • Hypospadias surgery outcomes require standardized measurement for consistent reporting.
  • A core outcome set (COS) aims to harmonize data collection across studies.
  • Addressing reporting heterogeneity is crucial for advancing clinical understanding.

Purpose of the Study:

  • To define a consensus-based core outcome set (COS) for hypospadias surgery.
  • To identify age-specific outcomes relevant to patients undergoing hypospadias repair.
  • To improve the quality and comparability of research data in hypospadias surgery.

Main Methods:

  • A three-round Delphi survey was employed, involving healthcare professionals, parents, and patients.
  • Participants ranked and selected preferred outcomes for different age groups.
  • Outcomes achieving over 70% consensus were designated as core outcomes.

Main Results:

  • Four core outcomes (voiding, fistula, re-operation, urethral stricture) were consistent for younger boys (<6 and 10-11 years).
  • Core outcomes for older boys (11-16 years and >16 years) included cosmesis, curvature, voiding, and psychosexual/psychosocial aspects, with variations.
  • Low response rates were noted among parents and patients.

Conclusions:

  • A core outcome set for hypospadias surgery shows consistency in younger age groups.
  • Greater variability in core outcomes for older boys suggests a need for further research and consensus.
  • The developed COS will aid in standardizing outcome assessment in hypospadias surgery research.