Biobanking of human teeth for stem cell storage: Preserving stem cells for future needs

Area of Science:

• * Regenerative Medicine
• * Stem Cell Biology
• * Dental Research

Background:

• * Human teeth contain postembryonic mesenchymal dental stem cells.
• * Seven types of dental stem cells identified in pulp and periodontal ligament.
• * These cells exhibit high proliferative capacity and broad clinical potential.

Purpose of the Study:

• * To review the process of dental stem cell biobanking.
• * To discuss isolation, cryopreservation, and therapeutic applications.
• * To highlight the potential of teeth as a biological resource.

Main Methods:

• * Narrative review of existing literature.
• * Focus on the workflow of teeth biobanking.
• * Examination of stem cell isolation and preservation techniques.

Main Results:

• * Dental stem cells from teeth show significant therapeutic promise.
• * Biobanking provides a method for long-term preservation.
• * Current biobanking efforts primarily focus on hematopoietic tissues.

Conclusions:

• * Extracted human teeth represent a valuable, underutilized resource for stem cell banking.
• * Teeth biobanking facilitates the isolation and preservation of dental stem cells.
• * These cells hold potential for future regenerative medicine and dentistry applications.