Missed and Delayed Diagnoses of Acute Human Immunodeficiency Virus (HIV) Infection in a Southern Opt-Out HIV Testing
Sarah F Gruber1, Eli P Wilber2,3, Brittany Smith3
1Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Open Forum Infectious Diseases
|January 20, 2025
Abstract:
Prompt confirmation of human immunodeficiency virus (HIV) is critical. We examined 10 years of discordant results without reflex HIV RNA. Of patients with acute HIV infection, 43.9% (95% confidence interval, 36.2%-52.0%) had confirmation delays >30 days or were never confirmed, indicating a need for reflex RNA to facilitate diagnosis.


