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Updated: May 26, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
Real-World Outcomes of Chemiluminescence Immunoassay Implementation for Mycobacterium tuberculosis Infection
Eli Wilber1,2, Marcos C Schechter1,2, Paulina A Rebolledo1,2,3
1Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
None:
Fully automated interferon gamma release assays based on chemiluminescence immunoassay promise more efficient testing for tuberculosis infection but increase rates of positive test results when compared with semiautomated assays. We report an increase in borderline-positive interferon gamma release assay results (87.8% relative increase; 95% CI, 31.1%-170.0%), which led to modifications in clinical care following chemiluminescence immunoassay implementation.
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