Macroscopic Hematuria Revealing Bladder Myeloid Sarcoma in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) can be presented with extramedullary manifestations, more frequently involving skin and rarely other sites, such as the urinary tract. We report the case of a 37-year-old male patient with a history of testicular cancer who presented to the emergency department with cytopenias and hematuria. Bone marrow analysis diagnosed AML (French-American-British(FAB) classificationM4 subtype, karyotype showing inv16). A diagnostic workup for hematuria revealed a bladder mass that underwent biopsy. Histopathology revealed myeloid sarcoma. The patient was treated with standard induction chemotherapy, followed by consolidation therapy including allogeneic stem cell transplantation, which resulted in complete remission of AML.