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Updated: Jun 1, 2025

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
Published on: February 25, 2011
Training T-shaped translational scientists.
Molly Wasko1, Kathryn Allen Nearing2,3, Stacey L Neves4
1Center for Clinical and Translational Science, University of Alabama at Birmingham, Birmingham, AL, USA.
The I-Corps@NCATS program enhances translational science by teaching scientific translation processes and fostering key scientist characteristics. This training accelerates the journey of research ideas into real-world solutions.
Area of Science:
- Translational Science
- Scientist Training
- Medical Research
Background:
- Translational scientists are crucial for moving research discoveries to clinical application.
- Key characteristics include systems thinking, process innovation, boundary spanning, teamwork, and communication.
- The I-Corps@NCATS program aims to cultivate these essential traits.
Purpose of the Study:
- To evaluate the I-Corps@NCATS program's effectiveness in developing translational scientist characteristics.
- To assess the program's impact on participants' skills in systems thinking, process innovation, boundary spanning, teamwork, and communication.
Main Methods:
- A mixed-methods evaluation was employed across 22 Clinical and Translational Science Award (CTSA) Hubs.
- Survey items assessed self-reported abilities related to core translational scientist characteristics.
- Open-ended comments were coded to identify shifts in translational orientation and additional characteristics.
Main Results:
- Participants reported the greatest gains in systems thinking and skilled communication abilities.
- Highest self-assessed abilities were in teamwork and boundary spanning.
- Intellectual humility and cognitive flexibility were identified as additional key characteristics.
Conclusions:
- I-Corps@NCATS accelerates translational science by imparting knowledge of the translation process.
- The program fosters the development of a translational scientist mindset and essential characteristics.
- This training supports the progression of research from concept to practical application.
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