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Updated: Jun 1, 2025

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood
Published on: February 11, 2017
Irritability as a Transdiagnostic Construct Across Childhood and Adolescence: A Systematic Review and Meta-analysis
Miriam Chin1, Davina A Robson2,3, Hannah Woodbridge1
1School of Psychology, The University of Sydney, Sydney, NSW, 2006, Australia.
Irritability in children and adolescents is linked to more severe mental health symptoms. This connection holds across various disorders, suggesting irritability is a key indicator of emotional dysregulation.
Area of Science:
- Child and Adolescent Psychiatry
- Developmental Psychology
- Clinical Psychology
Background:
- Irritability is a common symptom in childhood and adolescence.
- Its association with various mental health disorders requires further investigation.
- Understanding this relationship is crucial for early intervention.
Purpose of the Study:
- To examine irritability's association with mental health disorder symptoms in youth.
- To determine if this association varies by symptom domain (internalizing vs. externalizing, specific disorders).
- To explore potential moderators of the irritability-symptom severity relationship.
Main Methods:
- Meta-analytic review following PRISMA guidelines.
- Systematic search of five databases for studies on irritability and mental health symptoms in 2-18 year olds.
- Meta-analytic tests and meta-regression to analyze associations and moderators.
Main Results:
- A moderate, positive association between irritability and concurrent psychopathology severity was found.
- Small to moderate effect sizes linked irritability to later mental health outcomes.
- Significant variation in associations was observed across diagnostic domains and methodological factors.
Conclusions:
- Irritability is a transdiagnostic construct reflecting emotion dysregulation in youth.
- It is associated with both current and future mental health issues.
- Further research on risk mechanisms and early intervention strategies for irritability is warranted.
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