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Related Experiment Video

Updated: Jun 1, 2025

Simultaneous Electroencephalography, Real-time Measurement of Lactate Concentration and Optogenetic Manipulation of Neuronal Activity in the Rodent Cerebral Cortex
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SyncGenie: A programmable event synchronization device for neuroscience research.

Ludvik Alkhoury1, Giacomo Scanavini1, Petras Swissler2

  • 1Department of Radiology, Weill Cornell Medicine, New York, NY, 10065, USA.

Hardwarex
|January 21, 2025
PubMed
Summary
This summary is machine-generated.

Researchers developed SyncGenie, a low-cost, programmable device for synchronizing neural data with experimental events. This trigger box enhances neuroscience research by offering flexible, cost-effective event detection and data alignment.

Keywords:
Auditory and visual stimuliElectroencephalogramEvent Related Potentials (ERP)Event timingMultimodalityNeuroscienceStimulus synchronization and alignmentTrigger box

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Signal Processing

Background:

  • Precise synchronization between neural activity and experimental events is crucial in neuroscience.
  • Existing synchronization devices can be expensive and lack flexibility for diverse research needs.

Purpose of the Study:

  • Introduce SyncGenie, a programmable, cost-effective synchronization device for neuroscience research.
  • Provide open-access hardware designs and software for building and utilizing SyncGenie.
  • Demonstrate SyncGenie's utility as a trigger box, digitizer, and for real-time signal analysis.

Main Methods:

  • Designed a programmable synchronization device (SyncGenie) with easy-to-manufacture circuit boards and components.
  • Developed an Arduino library for user-friendly, code-free adjustments and programmability.
  • Integrated various connectors (3.5 mm TRS, D-sub25, BNC, JST-XH) for broad compatibility.

Main Results:

  • SyncGenie supports both hardware- and software-triggered pulse synchronization.
  • The device functions as a cost-effective digitizer for real-time analog signal analysis.
  • Open-access design files and code enable DIY construction and customization.

Conclusions:

  • SyncGenie offers a flexible, affordable alternative to commercial synchronization devices in neuroscience.
  • The device's programmability and ease of use facilitate adaptation to various experimental protocols.
  • Open-source availability promotes wider adoption and innovation in neuroscience research tools.