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Published on: August 30, 2019
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Vestibular Function in Patients With Vestibular Neuritis Experiencing Prodromal Dizziness.
Chisato Fujimoto1, Keiko Sugasawa1, Kentaro Ichijo1
1Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Summary
Prodromal dizziness (PD) preceding vestibular neuritis (VN) may indicate peripheral vestibular lesions. This study found PD is significantly associated with abnormalities in the anterior semicircular canal (ASCC) function.
Area of Science:
- Neurology
- Otolaryngology
- Vestibular System Disorders
Background:
- The relationship between prodromal dizziness (PD) and peripheral vestibular lesions in vestibular neuritis (VN) remains unclear.
- Investigating this association can improve understanding of VN pathophysiology.
Purpose of the Study:
- To determine if the presence of prodromal dizziness (PD) is associated with the severity of vestibular dysfunction in patients with unilateral vestibular neuritis (VN).
Main Methods:
- Retrospective review of 88 unilateral VN patients with unilateral canal paresis.
- Utilized vestibular function tests: caloric testing, air-conducted sound cervical vestibular evoked myogenic potential (ACS cVEMP), bone-conducted vibration ocular vestibular evoked myogenic potential (BCV oVEMP), and video head impulse test (vHIT).
- Binomial logistic regression analyzed associations between PD, age, sex, disease duration, and vestibular dysfunction.
Main Results:
- 19% of VN patients reported prodromal dizziness (PD).
- No significant association was found between PD and abnormalities in ACS cVEMPs, BCV oVEMPs, or vHIT of the posterior or lateral semicircular canals.
- PD showed a significant positive association with vHIT abnormalities in the anterior semicircular canal (ASCC).
Conclusions:
- Prodromal dizziness (PD) in vestibular neuritis (VN) may be linked to peripheral vestibular lesions.
- Specifically, PD is associated with dysfunction in the anterior semicircular canal (ASCC).
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