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Feedback Regulation of Calcium Concentration

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...

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Electrifying the brain capillary Ca²⁺ signal

Manuel F Navedo¹, Madeline Nieves-Cintron¹, L Fernando Santana²

¹Department of Pharmacology, University of California Davis School of Medicine, Davis, CA 95616.

Proceedings of the National Academy of Sciences of the United States of America

|January 21, 2025

Summary

No abstract available in PubMed .

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