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Updated: Jun 1, 2025

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Published on: August 9, 2024
Ultrasound-guided peripheral intravenous access in adults: A randomized crossover controlled trial
Chia-Chi Kuo1, Wei-Jing Lee2, Ya-Ting Ke3
1Department of Nursing, Chang Gung University of Science and Technology, Chiayi Campus, Taiwan.
Ultrasound guidance significantly improves success rates and reduces attempts for difficult peripheral intravenous access. This evidence-based protocol enhances patient safety and nursing efficiency in critical care settings.
Area of Science:
- Medical Ultrasound
- Vascular Access
- Emergency Medicine
Background:
- Difficult peripheral intravenous access is a frequent challenge in emergency and critical care.
- It compromises timely treatment, patient safety, and increases healthcare costs.
- Repeated cannulation attempts strain nursing staff and resources.
Purpose of the Study:
- To develop an evidence-based ultrasound-guided peripheral intravenous access protocol.
- To evaluate the efficacy of ultrasound guidance for difficult intravenous access.
Main Methods:
- A randomized crossover study involving 36 adult volunteers with difficult venous access.
- Comparison of ultrasound-guided versus traditional blind peripheral intravenous access.
- Utilized a high-frequency ultrasound probe with a two-person scanning technique.
Main Results:
- Ultrasound guidance dramatically improved first attempt success rates (OR=10.97, p<0.0001).
- Overall success rates were significantly higher with ultrasound (OR=49.67, p<0.0001).
- The number of attempts was reduced by an average of 0.50 (p<0.0001).
Conclusions:
- An ultrasound-guided protocol effectively improves peripheral intravenous access in challenging cases.
- Recommends a two-person scanning method and rigorous training for clinical implementation.
- Addresses difficult access issues, reduces nursing burden, and enhances care quality.
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