Related Experiment Video
Updated: Jun 1, 2025
11:05
SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
Published on: February 6, 2021
14.4K
Clinical Variables Associated With Impaired Consciousness in Hospitalized COVID-19 Patients
Sandra Gomez-Paz1, Eric Lam1, Joshua Fogel2
1Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY, USA.
Journal of Community Hospital Internal Medicine Perspectives
|January 22, 2025
Summary
In COVID-19 patients, factors like age, BMI, and certain lab values, not disease severity, impact impaired consciousness (Glasgow Coma Scale). This aids early identification and treatment strategies.
Area of Science:
- Neurology
- Infectious Diseases
- Critical Care Medicine
Background:
- Impaired consciousness is a critical factor in COVID-19 patient outcomes.
- The Glasgow Coma Scale (GCS) is a key measure for assessing consciousness levels.
Purpose of the Study:
- To identify factors associated with impaired consciousness in COVID-19 patients.
- To analyze the relationship between demographics, comorbidities, disease severity, treatment, and laboratory values with GCS scores.
Main Methods:
- Retrospective study of 604 COVID-19 patients.
- Analysis of GCS nadir during hospitalization and GCS at discharge.
- Inclusion of demographic, comorbidity, disease severity, treatment, and laboratory data.
Main Results:
- Age and body mass index were linked to lower GCS scores.
- Sedation and glucose levels affected GCS during hospitalization.
- Sodium and BUN levels at specific times influenced GCS at discharge.
Conclusions:
- Demographics, comorbidities, treatment, and lab results, not disease severity, correlate with GCS in COVID-19.
- Findings support early identification and management of impaired consciousness in COVID-19 patients.
Keywords:
Altered level of consciousnessCovid-19Glasgow coma scaleNeurological manifestationsSedativesMore Related Videos
Related Concept Videos
01:23Acute Respiratory Failure-IV
125
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
125
01:30Pneumonia III: Complications and Assessment
153
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
153
01:30Pneumonia I: Introduction
205
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
205
01:24General Anesthesia: Overview
190
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
190
01:30Acute Respiratory Failure-III
153
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
153
01:21Acute Respiratory Failure-I
162
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
162