Related Experiment Video
Updated: Jun 1, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Persistent Gingival Bleeding Related to Periodontal Disease
Yosuke Iijima1, Miki Yamada1, Takumi Takahashi1
1Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JPN.
Abstract:
Objective More patients visit oral surgery outpatient clinics from evening to night to treat persistent gingival bleeding (PGB) related to periodontal disease (PD) (PD-PGB). Since there are few reports on PD-PGB, the present study performed a detailed characterisation of this disease. Materials and methods Patients who visited our oral surgery clinic between 1 January 2014 and 31 December 2022 to treat PD-PGB without trauma. Demographic data, systemic diseases and bleeding tooth characteristics were retrieved. The occurrence of systemic diseases was compared with that of the control group (patients consisting of temporomandibular joint dislocation and minor trauma). Results Among 295 patients with gingival bleeding (GB) unrelated to trauma, 193 patients (65.4%) showed postoperative bleeding, and 91 patients (30.1%) showed PD-PGB; 93.4% of patients over 60 years old showed PD-PGB. Patients in the PGB-RPD group showed a significantly higher percentage (57.1%) of taking anticoagulants and/or antiplatelets than the control group (24.2%) (P < 0.001) Significantly higher percentage of patients in the PGB-RPD group showed a significantly higher incidence of hypertension (68.1%) than the control group (34.1%) (P < 0.001). Bleeding is the most frequently observed in molars, with a depth of the pockets exceeding 4 mm. Conclusion PD-PGB accompanied by deep pockets was more common in older patients and aggravated by taking anticoagulants and/or antiplatelets and antihypertensives. PD-PGB is not rare, and periodontal maintenance, such as regular dental checks, is an important preventive measure.
Related Concept Videos
Tonsillitis II: Management
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Measurement of Blood Pressure
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.

