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Conversion to Glaucoma After Ocular Trauma in Pediatric Patients
Nur Cardakli1, Rujuta A Gore1,2, Courtney L Kraus1
1Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Vision (Basel, Switzerland)
|January 23, 2025
Summary
Pediatric glaucoma suspects with closed-globe injuries had higher rates of ocular hypertension and developed glaucoma. No open-globe injuries progressed to glaucoma, indicating a difference in outcomes based on injury type.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Glaucoma Research
Background:
- Outcomes for pediatric glaucoma suspects with ocular trauma history are largely unknown.
- This study focuses on the conversion rate to glaucoma in this specific patient group.
Purpose of the Study:
- To determine the rate of glaucoma development in pediatric patients with a history of ocular trauma.
- To compare outcomes between open-globe and closed-globe injuries in pediatric glaucoma suspects.
Main Methods:
- Retrospective case series of pediatric patients (2005-2016) with ocular trauma monitored as glaucoma suspects.
- Inclusion criteria: history of open- or closed-globe trauma.
- Data collected on injury type, treatment, and glaucoma development.
Main Results:
- 62 eyes from 62 pediatric patients were analyzed; 46.8% open-globe, 53.2% closed-globe injuries.
- Eyes with closed-globe injuries had higher rates of topical therapy for ocular hypertension (36.4% vs. 10.3%).
- Five eyes (8.1%) developed glaucoma, all with prior closed-globe injuries; 4 required glaucoma surgery. Most post-traumatic glaucoma cases (60%) had concurrent intraocular surgeries.
Conclusions:
- All pediatric glaucoma cases following trauma in this cohort resulted from closed-globe injuries.
- No cases of open-globe injury in pediatric glaucoma suspects progressed to glaucoma.
- Injury type significantly impacts glaucoma development risk in pediatric ocular trauma patients.
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