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Recent Status on Lactate Monitoring in Sweat Using Biosensors: Can This Approach Be an Alternative to Blood
Leonardo Messina1, Maria Teresa Giardi1,2
1Microsis srl, Via degli Olmetti, 8a, 00060 Formello, Italy.
Biosensors
|January 24, 2025
Summary
Lactate biosensors offer promising non-invasive detection in sweat for sports and clinical use. However, further research is needed to confirm the correlation between sweat and blood lactate levels.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Biochemistry
Background:
- Lactate is crucial for cellular energy metabolism and immune/inflammatory signaling.
- Non-invasive lactate monitoring in sweat is gaining interest for sports and clinical applications.
- Biosensors utilizing electrochemical methods and nanomaterials are key for this detection.
Purpose of the Study:
- To review biosensors for electrochemical lactate detection in sweat.
- To assess the feasibility and desirability of sweat lactate analysis.
- To identify key issues for future technological applications.
Main Methods:
- Review of recent studies on electrochemical biosensors for lactate.
- Analysis of innovative nanomaterials employed in lactate biosensors.
- Evaluation of data on sweat lactate detection methods.
Main Results:
- Electrochemical biosensors with nanomaterials show potential for sweat lactate detection.
- Sweat lactate analysis via biosensors is feasible and desirable.
- The correlation between sweat and blood lactate concentrations remains unclear.
Conclusions:
- Electrochemical biosensors are a viable tool for sweat lactate monitoring.
- Further studies are essential to validate sweat lactate as a biomarker.
- Clarifying sweat-blood lactate correlations is critical for clinical translation.
