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Social, Racial, and Economic Disparities Affecting Outcomes of Hypertensive Adolescents
Kanya Singhapakdi1, Amelia Haydel2, Marla Johnston1
1Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans, USA.
Social determinants of health significantly impact adolescent hypertension outcomes. Higher social vulnerability and lower income in pediatric patients were linked to increased left ventricular mass, highlighting the need for targeted interventions.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Health
- Public Health
Background:
- Essential hypertension is a prevalent condition in pediatric cardiology with significant long-term cardiovascular risks.
- Pediatric hypertension is recognized as a major public health challenge in the United States.
- Social determinants of health (SDH) encompass environmental factors influencing an individual's health outcomes.
Purpose of the Study:
- To investigate the impact of various social determinants of health on cardiovascular outcomes in adolescents with essential hypertension.
- To analyze the association between social vulnerability, income, race, and end-organ damage in pediatric hypertension.
Main Methods:
- Utilized validated tools from the U.S. Census and USDA to score patients' social vulnerability based on their home address.
- Compared social vulnerability scores with echocardiographic data, focusing on measures of hypertension-related end-organ damage.
- Specifically examined indexed left ventricular (LV) mass and left atrial (LA) volume as indicators of cardiovascular impact.
Main Results:
- Increased social vulnerability and lower income were significantly associated with greater indexed LV mass (r = 0.18, p = 0.008).
- African American race was associated with a higher LA volume (p = 0.03).
- These findings indicate that social constructs intersect with biological factors to affect cardiovascular health in adolescents.
Conclusions:
- Adolescents with essential hypertension experience cardiovascular effects influenced by a complex interplay of social and biological factors.
- The study underscores the importance of understanding social determinants in managing pediatric hypertension.
- Results provide a foundation for developing targeted interventions to improve clinical outcomes for vulnerable pediatric populations.
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