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Related Experiment Videos

The late asthmatic response.

R G Bhagat, R C Strunk, G L Larsen

    Annals of Allergy
    |April 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Late Asthmatic Reactions (LARs) increase airway reactivity for weeks after allergen exposure. Identifying allergic triggers through history and skin tests is crucial for managing LARs effectively.

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    Area of Science:

    • Allergy and Immunology
    • Pulmonary Medicine
    • Respiratory Medicine

    Background:

    • Late Asthmatic Reactions (LARs) are linked to increased airway reactivity.
    • This heightened reactivity can persist for weeks post-allergen exposure, extending beyond immediate symptoms.

    Observation:

    • Patients with suspected LARs require thorough investigation for allergic triggers.
    • Historical data and skin prick testing are vital diagnostic tools.
    • Bronchial challenge testing may be considered for environmental triggers when other methods fail.

    Findings:

    • Non-specific airway hyperresponsiveness in LARs may stem from airway inflammation.
    • Bronchial challenge carries risks, including transient airway inflammation, which must be weighed against diagnostic benefits.

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    Implications:

    • Accurate diagnosis of LARs is essential for effective management.
    • Allergen avoidance is the primary treatment strategy.
    • Prophylactic medications like cromolyn sodium are recommended when avoidance is not feasible.