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Equitable allocation through human leukocyte antigen eplet matching: A promising strategy with several challenges

Gonca E Karahan1, Geert W Haasnoot1, Sebastiaan Heidt2

  • 1Eurotransplant Reference Laboratory, Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|January 24, 2025
PubMed
Abstract

No abstract available in PubMed .

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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