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MUSCULOSKELETAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS.

Ljiljana Smiljanić Tomičević1, Marko Barešić1, Miroslav Mayer1

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Summary
This summary is machine-generated.

Systemic lupus erythematosus (SLE) frequently causes musculoskeletal issues like arthritis and myalgia, impacting patient quality of life. Early diagnosis via musculoskeletal ultrasound can improve treatment outcomes and prevent irreversible damage.

Keywords:
ArthritisMusculoskeletalMyositisSystemic lupus erythematosusUltrasound

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Area of Science:

  • Rheumatology
  • Immunology
  • Radiology

Background:

  • Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease predominantly affecting young, working women.
  • Musculoskeletal manifestations, including arthralgia, arthritis, myalgia, tenosynovitis, and enthesitis, are highly prevalent in SLE patients (over 90%).
  • These symptoms significantly impair patients' quality of life and daily functioning, despite not always being considered severe SLE features.

Purpose of the Study:

  • To highlight the importance of musculoskeletal manifestations in SLE diagnosis and management.
  • To emphasize the role of clinical assessment and imaging in evaluating musculoskeletal involvement.
  • To advocate for the use of accessible diagnostic tools like musculoskeletal ultrasound.

Main Methods:

  • Clinical assessment of joints, tendons, entheses, and muscles as the gold standard for diagnosis.
  • Utilizing various radiological imaging methods such as X-rays, ultrasound, bone scintigraphy, and MRI for morphological assessment.
  • Focusing on musculoskeletal ultrasound as a practical and cost-effective imaging modality.

Main Results:

  • Musculoskeletal symptoms are present in over 90% of SLE patients, significantly affecting daily life.
  • Radiological imaging provides crucial morphological information on disease activity and damage.
  • Musculoskeletal ultrasound is identified as an accessible and affordable diagnostic tool.

Conclusions:

  • Recognizing musculoskeletal manifestations is key for early SLE diagnosis and assessing disease activity.
  • Early diagnosis and treatment initiation based on musculoskeletal findings can prevent chronic, irreversible changes.
  • Utilizing tools like musculoskeletal ultrasound can lead to improved patient quality of life through timely intervention.