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Biofunctionalization of Magnetic Nanomaterials
Published on: July 16, 2020
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Bioactive surface-functionalized MXenes for biomedicine.
Ting Li1, Weipeng Qiang1, Bo Lei1,2,3
1Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710054, China. rayboo@xjtu.edu.cn.
Nanoscale
|January 28, 2025
Summary
MXenes, nanomaterials with excellent biocompatibility and bioactivity, show promise for tissue regeneration. Surface modification creates multifunctional MXene biomaterials for diverse biomedical applications, advancing nanomedicine translation.
Area of Science:
- Biomaterials Science
- Nanomedicine
- Tissue Engineering
Background:
- MXenes possess advantageous biocompatibility, photovoltaic, physicochemical, and bioactive properties.
- Current applications span biosensing, bioimaging, therapy (tumor/infection), bone regeneration, and wound repair.
- Surface modification of MXenes with bioactive materials yields multifunctional nanomaterials.
Purpose of the Study:
- To review existing research on MXene bioactivities.
- To summarize surface modification strategies for MXenes.
- To explore the biomedical applications of MXene-based nanomaterials.
Main Methods:
- Literature review of studies on MXene bioactivities.
- Analysis of surface modification techniques for MXenes.
- Compilation of data on MXene applications in biomedicine.
Main Results:
- MXenes exhibit significant potential in tissue regeneration due to their inherent properties.
- Surface functionalization enhances MXene capabilities for targeted biomedical uses.
- A wide array of applications, including regenerative medicine and therapeutics, are demonstrated.
Conclusions:
- MXene-based biomaterials offer versatile platforms for advanced biomedical applications.
- Further development of well-designed MXene nanomaterials is crucial for clinical translation.
- This review provides insights into the future prospects of MXenes in nanomedicine.

