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Receptor-ligand interactions for optimized endocytosis in targeted therapies

Yejin Sung1, Youngjin Choi1, Eun Sun Kim2

  • 1Medicinal Materials Research Center, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|January 28, 2025
PubMed
Summary

Receptor-mediated endocytosis is key for drug development, controlling how therapies enter cells. Understanding receptor-ligand interactions allows precise control over cellular trafficking for enhanced therapeutic efficacy.

Keywords:
Antibody drug conjugateEndocytosisReceptor internalizationReceptor ligand interactionTargeted protein degradation

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