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Multi-site enzymatic repairing amplification (MSERA) enables ultrasensitive detection of terminal deoxynucleotidyl

Dianming Zhou1,2,3,4, Tao Meng5, Dalong Zhang2,3

  • 1Department of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin, China. fangzhongze@tmu.edu.cn.

Chemical Communications (Cambridge, England)
|January 29, 2025
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Long-patch Base Excision Repair01:02

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Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are: