Vaccine-Induced Annular Atrophic Lichen Planus

Area of Science:

• Dermatology
• Immunology
• Vaccinology

Background:

• Annular atrophic lichen planus (AALP) is a rare, chronic subtype of lichen planus.
• AALP typically shows resistance to conventional topical steroid treatments.
• The precise pathogenesis of AALP, potentially involving dermal inflammatory responses, is not fully understood.

Purpose of the Study:

• To report a rare case of AALP developing post-vaccination.
• To discuss the potential link between vaccination and AALP development.
• To review factors influencing AALP and its treatment response.

Main Methods:

• Case study presentation.
• Clinical observation of lesion development and progression.
• Review of existing literature on vaccine-induced lichen planus and AALP.

Main Results:

• A 54-year-old female developed AALP lesions on her trunk and extremities after vaccination.
• The patient's condition was confirmed approximately one year after symptom onset.
• The case illustrates a rare instance of vaccine-associated dermatological reaction.

Conclusions:

• Vaccination can be a rare trigger for lichen planus, including the AALP subtype.
• AALP presents a diagnostic and therapeutic challenge due to its resistance to standard treatments.
• Further investigation into vaccine-induced AALP is warranted to understand its pathogenesis and optimize management.