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Updated: May 30, 2025

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
Clinical, Laboratory, and Trichoscopic Features of Pediatric Androgenetic Alopecia
Changpei Lu1, Yige Fan1, Yimei Du1
1Drs. Lu, Du, Zhao, and Fan and Lingbo Bi, Chaofan Wang, and Yunbu Ding are from the Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, China. Yige Fan is from the Mayo Clinic, Rochester, Minnesota.
Abstract:
In this retrospective study, we analyzed the prevalence and impact of pediatric androgenetic alopecia (AGA). Over a 14-year period, 133 pediatric patients were evaluated, with manifestations of AGA appearing as early as age 10 years. The analysis included factors such as body mass index (BMI), family history of AGA, comorbidities, laboratory results, and patterns of hair loss. Trichoscopic differences between sexes and age groups were observed. This study underscores the importance of individualized, step-by-step, and comprehensive treatment for pediatric AGA, prioritizing hormonal disorders and concurrent conditions while managing hair loss with topical minoxidil. Topical minoxidil generally is well tolerated in pediatric patients, although close monitoring of adverse effects and timely feedback to the clinician still are necessary. More importantly, encouraging patients to adhere to their medication and attend regular follow-up appointments can yield favorable outcomes.
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