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Updated: May 30, 2025
![An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F66708.jpg&w=3840&q=50)
An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
68 Ga-FAPI-04 Versus 18 F-FDG PET/CT in Duodenal Synovial Sarcoma
Fenglin Zhan1, Xin Liu, Hangcheng Zhou
1Departments of Nuclear Medicine, and Pathology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Abstract:
A previously healthy 18-year-old man with a 9-month history of upper abdominal pain and significant weight loss underwent gastroscopy, revealing an ulcerative lesion in the duodenal bulb. Enrolled in a clinical trial, both 18 F-FDG and 68 Ga-FAPI-04 PET/CT demonstrated similar metabolic activity, though 68 Ga-FAPI-04 offered superior lesion delineation. Pathology confirmed synovial sarcoma. This case highlights the potential utility of 68 Ga-FAPI-04 as a radiopharmaceutical for evaluating rare gastrointestinal synovial sarcomas.
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