Related Experiment Video
Updated: May 30, 2025

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Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
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Long-term Outcomes After Minimally Invasive Ventral Rectopexy for Rectal Prolapse Using Biological Graft Prosthesis:
Michael L R Lonne1,2, Amy M Y Cao1, Ashley Jenkin1,2
1Department of Surgery, Division of Colorectal Surgery, The Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Diseases of the Colon and Rectum
|January 30, 2025
Summary
Minimally invasive ventral rectopexy using biological grafts is safe and effective for prolapse repair. This study found acceptable recurrence rates and low complications, with no graft-related issues reported.
Area of Science:
- Colorectal surgery
- Pelvic floor disorders
- Surgical innovation
Background:
- Minimally invasive ventral rectopexy is a preferred prolapse procedure.
- Concerns exist regarding synthetic mesh safety in pelvic surgery.
- Data on biological graft safety and repair longevity are limited.
Purpose of the Study:
- To evaluate the short- and long-term safety and efficacy of biological grafts in minimally invasive ventral rectopexy.
- To assess recurrence rates and complications associated with biological graft use.
- To determine functional outcomes and patient satisfaction after the procedure.
Main Methods:
- Retrospective cohort study utilizing prospectively collected data.
- Analysis of 366 patients undergoing minimally invasive ventral rectopexy with biological grafts.
- Minimum 6-month follow-up from January 2008 to October 2023.
Main Results:
- Overall recurrence rate was 15.6% (57/366) with 1-, 3-, and 5-year estimates of 2.0%, 6.0%, and 16.0% respectively.
- 34 complications occurred in 29 patients (7.9%), with 5.2% requiring reoperation; no graft-related complications or long-term pain were reported.
- 98% of patients reported symptomatic improvement and satisfaction with outcomes.
Conclusions:
- Minimally invasive ventral rectopexy with biological grafts demonstrates safety and efficacy.
- Acceptable short- and long-term recurrence rates and overall complication profiles were observed.
- Biological grafts offer a safe alternative with no associated graft-related morbidity.

