Related Experiment Video
Updated: May 30, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Unearthing the Unexpected: First Report of Ossa Cordis in a Human Heart
Mehrnoosh Ghandili1, Mark A Giffen
1Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC.
Insights
The ossa cordis (cardiac bone) was incidentally found in a human heart, marking its first documented occurrence in humans. This bony structure, typically seen in large mammals, raises questions about its role in human cardiac anatomy and development.
Area of Science:
- Anatomy
- Cardiology
- Pathology
Background:
- The ossa cordis (OC), or cardiac bone, is a mammalian cardiac skeleton structure.
- OC is found in large mammals and recently in chimpanzees, but not previously in humans.
- Its function is thought to maintain heart shape and enhance contraction efficiency.
Purpose of the Study:
- To report the incidental finding of ossa cordis in a human heart.
- To describe the characteristics and location of the OC.
- To discuss the implications for human cardiac anatomy and development.
Main Methods:
- Postmortem examination of a 39-year-old male heart.
- Gross examination and measurement of the bony structure.
- Histological analysis of the bone and surrounding tissue.
Main Results:
- An incidental 0.8 × 0.6 × 0.4-cm, boomerang-shaped ossa cordis was found.
- The OC was located in the right atrium, within the triangle of Koch, at the atrioventricular node.
- Histology confirmed mature bone with trilineage hematopoietic elements.
Conclusions:
- This is the first reported case of ossa cordis in a human.
- The finding suggests anatomical similarities between human and other mammalian hearts.
- Further research is needed to determine if OC in humans is linked to degenerative disorders or normal development/aging.
Abstract:
The ossa cordis (OC), or cardiac bone, is a bony structure within the cardiac skeleton of mammals, believed to maintain heart shape during systole and enhance contraction efficiency. Found in large mammals, especially ruminants, and has recently been described in chimpanzees; however, OC has not previously been described in humans. Herein, we present an incidental finding of OC in the heart of a 39-year-old man who suffered a stab wound to chest. A thorough postmortem examination revealed a 0.8 × 0.6 × 0.4-cm, well-defined, boomerang-shaped, bony structure embedded in atrioventricular node location in the right atrium within the triangle of Koch. The heart showed cardiomegaly and moderate atherosclerosis in the left anterior descending and right coronary arteries but was otherwise normal, without fibrosis, valvular abnormalities, or degenerative changes. Histological analysis revealed mature bone with trilineage hematopoietic elements. This finding highlights anatomical similarities between human hearts and other species, raising questions about whether OC in humans and primates is linked solely to degenerative cardiac disorders or represents a normal aspect of mammalian heart development and aging. To our knowledge, this is the first reported case of an OC in a human.
Related Concept Videos
Development of the Heart
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
Anatomy of the Heart
Heart Sounds
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Thoracic Aorta
Conduction System of the Heart
This system relies on the unique properties of nodal and Purkinje cells:...

