Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infertility in Males01:23

Infertility in Males

238
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
238
Spermatogenesis01:41

Spermatogenesis

102.0K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.0K
Metabolic States of the Body: Fasting and Starvation01:24

Metabolic States of the Body: Fasting and Starvation

1.1K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
1.1K
Infertility in Females01:28

Infertility in Females

269
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
269
Birth Control Methods01:22

Birth Control Methods

173
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
173

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early but not late time-restricted eating improves an actigraphy-estimated sleep quality in women with overweight or obesity: secondary analysis of the crossover ChronoFast trial.

Frontiers in nutrition·2026
Same author

Fathers' perspectives on the breastfeeding experience: a qualitative study.

Frontiers in nutrition·2026
Same author

Correction: Effect of the health and wellness Kneipp concept on health promotion and reduction of sick days for kindergarten children: a cluster randomized controlled trial protocol.

Frontiers in medicine·2026
Same author

The social structure of attitudes towards conventional and unconventional medicine and their relation to health behavior.

Journal of health psychology·2026
Same author

Editorial: The increasing relevance of traditional medicine systems for the primary health care sector and general practice: global research perspectives, volume II.

Frontiers in medicine·2026
Same author

When "CAM" is not CAM: Interpreting national cancer database analyses in breast cancer.

The oncologist·2026

Related Experiment Video

Updated: May 30, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
08:06

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

8.8K

Fasting for male fertility-a mixed methods study.

Katharina T May1, Jocelyn Behling1, Katharina Sochiera-Plegniere1

  • 1Institute of Social Medicine, Epidemiology, and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Frontiers in Nutrition
|January 31, 2025
PubMed
Summary

The Fasting Mimicking Diet (FMD) is feasible for men with subfertility, showing potential positive trends in sperm quality and increased self-efficacy. Further research is needed to confirm these effects.

Keywords:
fastinghealthy lifestyleinfertilitymalesemen analysissperm motility

More Related Videos

A Method to Test the Effect of Environmental Cues on Mating Behavior in Drosophila melanogaster
08:13

A Method to Test the Effect of Environmental Cues on Mating Behavior in Drosophila melanogaster

Published on: July 17, 2017

9.0K
Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
08:48

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects

Published on: April 21, 2022

2.3K

Related Experiment Videos

Last Updated: May 30, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
08:06

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice

Published on: November 27, 2019

8.8K
A Method to Test the Effect of Environmental Cues on Mating Behavior in Drosophila melanogaster
08:13

A Method to Test the Effect of Environmental Cues on Mating Behavior in Drosophila melanogaster

Published on: July 17, 2017

9.0K
Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
08:48

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects

Published on: April 21, 2022

2.3K

Area of Science:

  • Reproductive Medicine
  • Metabolic Research
  • Nutritional Science

Background:

  • Male subfertility affects 10-20% of couples, with male factors contributing to 50% of cases.
  • Preclinical research suggests fasting may influence spermatogenesis.
  • Investigating novel interventions for male infertility is crucial.

Purpose of the Study:

  • To assess the feasibility of a Fasting Mimicking Diet (FMD) in men with impaired sperm quality.
  • To explore the effects of FMD on key sperm parameters.
  • To evaluate participants' experiences and self-efficacy regarding fertility.

Main Methods:

  • Two-arm, randomized, controlled, exploratory mixed-methods study.
  • Fasting group: 5-day FMD (500 kcal/day) thrice over 4 months.
  • Control group: Maintained normal lifestyle and diet. Sperm quality assessed by WHO criteria.

Main Results:

  • Recruitment was challenging; 18 of 22 participants completed the study.
  • No significant between-group differences in sperm parameters were observed.
  • Slight positive trends favored the FMD group for motility and count; qualitative data indicated FMD feasibility and improved self-efficacy.

Conclusions:

  • The FMD is feasible for men experiencing subfertility.
  • While not statistically significant, trends suggest potential benefits for sperm quality.
  • FMD may enhance self-efficacy and promote healthier lifestyle choices in men with fertility concerns.