Related Experiment Video
Updated: Jul 8, 2026

10:05
Trichuris muris Infection: A Model of Type 2 Immunity and Inflammation in the Gut
Published on: May 24, 2011
16.3K
An ascaris twist.
1George Regional Hospital, South Africa.
Summary
Ascaris lumbricoides can cause life-threatening small bowel volvulus in children. Prompt surgical intervention is crucial for suspected worm bolus complications like peritonism and acidosis to prevent perforation.
Area of Science:
- Medical Parasitology
- Pediatric Surgery
- Gastrointestinal Emergencies
Background:
- Ascariasis, caused by Ascaris lumbricoides, is a common intestinal parasite, particularly in resource-limited settings.
- While often asymptomatic or causing mild symptoms, Ascaris infections can lead to severe gastrointestinal complications.
Purpose of the Study:
- To report a case of pediatric small bowel obstruction and volvulus caused by an Ascaris worm bolus.
- To emphasize the critical, life-threatening potential of Ascaris worm bolus complications.
Main Methods:
- Case report of a five-year-old male presenting with symptoms of small bowel obstruction.
- Diagnostic imaging including plain abdominal radiography to identify a worm bolus.
- Surgical exploration (laparotomy) due to peritonism and acidosis.
Main Results:
- A large Ascaris worm bolus was identified as the cause of small bowel volvulus.
- A segment of necrotic small bowel was present due to the volvulus.
- Successful surgical management involved detorsion and resection of the affected segment.
Conclusions:
- Small bowel volvulus due to an Ascaris worm bolus is a rare but life-threatening complication.
- Vigilant observation for signs of sepsis, acidosis, and peritonism is essential in suspected cases.
- Early surgical intervention is critical to prevent morbidity and mortality associated with perforation.
Related Concept Videos
Angle of Twist: Problem Solving
An electric motor applies a torque of 700 N·m to an aluminum shaft, triggering a stable rotation. Two pulleys, B and C, are subjected to torques of 300 N·m and 400 N·m, respectively. The modulus of rigidity is provided as 25 GPa. With the knowledge of the length and diameter of each segment, the twist angle between the two pulleys can be computed. First, a section cut is made between pulleys B and C, and the cut cross-section is analyzed using a free-body diagram. Given that the torque exerted...
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...

