Two new phenolic constituents from the Aconitum pendulum Busch roots
Min Ma1, Sifan Liu2, Dan Dong1
1Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, Qinghai MinZu University, Xining, China.
Natural Product Research
|January 31, 2025
Abstract
None:
Two new phenolic compounds aconitol A (1) and B (2), together with three known compounds including one phenolic constituent (3) and two diterpenoid alkaloids (4-5), were isolated from the roots of Aconitum pendulum. Their structures were assigned by HRESIMS, extensive spectral methods and compared with literature data. All obtained compounds (1-5) were tested for their inhibitory activity against NO production in LPS-activated RAW 264.7 macrophages. Compound 1 and 5 showed moderate inhibitory effects.
