[Halo nevi and vitiligoid phenomena in a case of melanoma]

This paper reports a case of malignant Melanoma in a 53 year old man with simultaneous development around the lesion of an acromic area with the characteristics of the so called Halo Navi phenomenon. Furthermore the patient presented lesions in other skin areas not related to apparent nevi. Microscopic tissue examination showed an inflammatory infiltrate in the depigmented zone which tended to surround and to include the melanoma periphery. This supports the conclusions of other publications linking these infiltrates with immunological phenomena tending to eliminate the tumor. A review is made of the new physiopathogenic criteria of the development of vitiligo.