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Monkeypox Outbreak 2023 in Chengdu, China: an Observational Study
Lang Rao1, Mei Yang1, Li-Yu Chen2
1Department of Dermatology, Chengdu Second People's Hospital, China.
Japanese Journal of Infectious Diseases
|February 2, 2025
Summary
Monkeypox cases in Chengdu, China, primarily affected men who have sex with men (MSM), presenting with characteristic skin lesions. The study highlights the need for public health surveillance of this emerging zoonotic viral disease.
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Monkeypox, a zoonotic viral disease, was historically endemic to Africa but has recently seen a global surge since May 2022.
- Sporadic imported cases of monkeypox have been confirmed in China, necessitating local epidemiological investigation.
Purpose of the Study:
- To investigate the clinical and epidemiological characteristics of monkeypox cases in Chengdu, southwest China.
- To understand the transmission patterns and risk factors associated with monkeypox in the region.
Main Methods:
- Retrospective analysis of clinical and epidemiological data from 28 confirmed monkeypox cases in Chengdu.
- Detailed examination of symptoms, lesion distribution, and patient demographics, including sexual orientation and history of sexually transmitted diseases.
Main Results:
- All 28 confirmed cases were male, with 26 identifying as men who have sex with men (MSM).
- Common symptoms included papules, pustular papules, vesicles, scabs, and ulcerations, predominantly in the anogenital and perineal areas; three cases had widespread exanthems.
- Seven patients had a history of sexually transmitted diseases; no hospitalizations or deaths were reported. Three instances of secondary transmission occurred among sexual partners.
Conclusions:
- The findings underscore the prevalence of monkeypox among MSM in Chengdu and emphasize the importance of targeted public health surveillance.
- Understanding the clinical presentation and transmission dynamics is crucial for effective public health response and risk communication for this emerging zoonotic viral disease.
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