Related Experiment Video
Updated: May 29, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Fracture-Related Infections in the Foot and Ankle
Alexandra N Krez1, Albert T Anastasio1, Samuel B Adams2
1Department of Orthopedic Surgery, Duke University Hospital, 2301 Erwin Road, Durham, NC 27710, USA.
Abstract:
Fracture-related infection (FRI) poses significant challenges in the management of foot and ankle fractures, potentially leading to functional impairment and heightened health care expenses. This review addresses the diagnosis, risk factors, and management strategies for FRI. Surgical management involves multidisciplinary collaboration, emphasizing debridement, antimicrobial therapy, and implant removal when indicated. Specific considerations for limited soft tissue coverage, tenuous blood supply, and fracture type in the foot and the ankle underscore the importance of tailored approaches to optimize outcomes and reduce complications in FRI management.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Ankle Joint
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Bones of the Lower Limb: Tibia and Fibula
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

