Related Experiment Video
Updated: May 29, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Incidence and mortality by pulmonary tuberculosis in Brazil: Trends and projections, 2002-2034
Jefferson Felipe Calazans Batista1, Vitória Steffany de Oliveira Santos1, Marcos Antonio Almeida-Santos1
1Tiradentes University, Health and Environment Post-graduation Program, Aracaju, Sergipe, Brazil.
Objectives:
To analyze the temporal trend of incidence and mortality from pulmonary tuberculosis in Brazil from 2002 to 2019 and to project these trends until 2034.
Methods:
Ecological study with tuberculosis cases extracted from the Disease Notification and Mortality System in Brazil from 2002 to 2019. The age-period-cohort model was used for projection until 2034 using R. Subsequently, the percentage variation was estimated using Joinpoint.
Results:
Brazil recorded 1,093,070 new cases and 76,205 deaths from 2002 to 2019, and projections until 2035-2034 estimated 1,192,092 new cases and 67,532 deaths. The north region had the highest standardized incidence and mortality rates in the country for both sexes. An increase in deaths in men and reduction in women was projected, along with an increase in incidence in both sexes. About 36% of the increase in incidence and 34.1% of the mortality in men was explained by a rise in disease risk. In women, 11.7% of the increase in incidence was due to population growth, whereas 44.8% of the reduction in deaths was due to lower risk.
Conclusions:
The north presented the worst scenario in the country. The projections are not favorable to the globally established targets. An increase in incidence was projected for men and women, with an increase in deaths only in men. More efforts are needed to change this potential scenario.
Related Concept Videos
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...

