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Updated: May 29, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Effect of home environment on neuropsychiatric development in preterm infants discharged from NICU at 18 months
Yuan Tian1, Chuncao Zhang2, Feng Liu1
1Department of Child Health Care, Shanghai Children's Hospital, Shanghai, China.
Insights
A supportive home environment significantly improves neuropsychological development in preterm infants, reducing risks of developmental delays. Prioritizing home environment assessment and enhancement is crucial for optimal outcomes in these vulnerable infants.
Area of Science:
- Neonatal Development
- Pediatric Neuropsychology
- Environmental Influences on Child Development
Background:
- Limited research exists on the home environment's impact on preterm infant development.
- The specific aspects and extent of home environment influence on early neuropsychological outcomes remain unclear.
Purpose of the Study:
- To analyze the effect of the home environment on preterm infants' neuropsychiatric development at 18 months corrected age.
- To establish a basis for improving preterm infant neurodevelopment through home environment interventions.
Main Methods:
- Retrospective cross-sectional study of 275 preterm infants discharged from the NICU.
- Home Nurture Environment Questionnaire used to assess the home environment.
- Gesell Developmental Scale evaluated developmental quotient and delays at 18 months corrected age.
Main Results:
- Infants in moderate/unsupportive home environments had significantly higher risks of developmental delay (global, fine motor, language, personal-social).
- Language and adaptive domains showed the highest rates of developmental delay.
- Supportive home environments were associated with better neurodevelopmental outcomes.
Conclusions:
- A supportive home environment is a critical protective factor for preterm infant neurodevelopment.
- Higher developmental quotient scores and protection against delays are linked to nurturing home settings.
- Integrating home environment assessment into preterm infant care management is essential for optimal neurodevelopment.
Background:
There have been numerous intervention studies focusing on the development of preterm infants, but there has been limited investigation into the home environment as a determinant of developmental outcomes in preterm infants. The aspects and extent to which the home environment affects the early (18 months corrected age) neuropsychological development of preterm infants are still unclear.
Aims:
This study aimed to analyse the effect of the home environment on the neuropsychiatric development of preterm infants at 18 months corrected age after discharge from the neonatal intensive care unit (NICU). It also sought to provide a basis for promoting neuropsychiatric development among preterm infants by improving the home environment.
Methods:
In this retrospective cross-sectional study, 275 preterm infants born between January 2019 and January 2022 were followed up for systematic management after discharge from the NICU at Shanghai Children's Hospital. The Home Nurture Environment Questionnaire was used to assess the home environment of the infants and analyse its impact on the developmental quotient (evaluated by the Gesell Developmental Scale) and the rate of developmental delays at 18 months corrected age.
Results:
A total of 41.454% of the infants were extremely preterm. The developmental quotient scores at 18 months corrected age were in the middle of the scale. The language domain had the highest rate of developmental delay (46.182%), followed by the adaptive domain (37.091%). Multiple logistic regression analyses showed that compared with infants in supportive home environments, infants with moderate/unsupportive home environments had significantly elevated risks of development delay: 2.162-fold for global (odds ratio (OR) 2.162, 95% confidence interval (CI) 1.274 to 3.665, p=0.004), 2.193-fold for fine motor (OR 2.193, 95% CI 1.161 to 4.140, p=0.016), 2.249-fold for language (OR 2.249, 95% CI 1.336 to 3.786, p=0.002) and 2.042-fold for personal-social (OR 2.042, 95% CI 1.149 to 3.628, p=0.015).
Conclusions:
A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants. It is associated with higher developmental quotient scores and protects against neuropsychiatric delays. Incorporating evaluation and continuous improvement of the home environment into the management framework for preterm infants to promote optimal neurodevelopment is essential.
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