Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Visual System01:26

Visual System

484
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
484

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validity and Reliability of the CVI Range for Clinical Research: Baseline and One-Year Results.

Ophthalmology science·2026
Same author

COG5-congenital disorder of glycosylation diagnosed by whole genome sequencing in siblings with unexplained optic atrophy, macular atrophy, and developmental delay: case report.

Frontiers in neurology·2026
Same author

Task-Preserving EEG Anonymization Using Latent Feature Masking.

IEEE journal of biomedical and health informatics·2026
Same author

Ghost poisoning: Making users invisible to speaker verification models.

JASA express letters·2026
Same author

Temporal patterns in articulation underlying repetitions, prolongations and blocks.

Journal of fluency disorders·2026
Same author

Neural Responses to Affective Sentences Reveal Signatures of Depression.

Translational psychiatry·2026

Related Experiment Video

Updated: May 29, 2025

Author Spotlight: An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System
05:10

Author Spotlight: An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System

Published on: March 17, 2023

2.6K

Method for assessing visual saliency in children with cerebral/cortical visual impairment using generative artificial

Kate Matsunaga1, Kleanthis Avramidis2, Mark S Borchert1,3

  • 1Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

Frontiers in Human Neuroscience
|February 3, 2025
PubMed
Summary

A new AI-powered eye-tracking method objectively quantifies visual processing deficits in children with cerebral/cortical visual impairment (CVI). This approach can guide interventions and clinical trials for pediatric visual impairment.

Keywords:
cerebral visual impairmentcortical visual impairmenteye trackingfunctional vision assessmentgenerative artificial intelligence

More Related Videos

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

284
Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
06:37

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

Published on: December 15, 2023

2.6K

Related Experiment Videos

Last Updated: May 29, 2025

Author Spotlight: An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System
05:10

Author Spotlight: An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System

Published on: March 17, 2023

2.6K
Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

284
Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
06:37

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

Published on: December 15, 2023

2.6K

Area of Science:

  • Ophthalmology and Neuroscience
  • Artificial Intelligence in Healthcare
  • Pediatric Visual Impairment Research

Background:

  • Cerebral/cortical visual impairment (CVI) is a primary cause of vision loss in children, particularly those who are premature or developmentally delayed.
  • Current diagnostic methods lack objective standardization for assessing diverse visual impairments in young children with CVI.
  • There is a critical need for precise tools to evaluate visual processing abnormalities in pediatric CVI.

Purpose of the Study:

  • To introduce and validate a novel method combining eye tracking and generative AI (SegCLIP) for objective assessment of visual characteristics in children with CVI.
  • To compare visual processing patterns between children with CVI and neurotypical controls using AI-generated saliency maps and eye-tracking data.
  • To correlate objective fixation saliency values with functional vision assessments (CVI Range-CR) for clinical relevance.

Main Methods:

  • Recruitment of 40 children with CVI and 40 age-matched controls (12 months to 12 years).
  • Utilizing eye tracking to record gaze position while participants view standardized images.
  • Employing SegCLIP AI to generate saliency maps, which are then compared with eye-tracking fixation maps to derive fixation saliency values.

Main Results:

  • Anticipated lower fixation saliency values for higher-level visual processing in CVI participants compared to controls.
  • Expected similar or higher fixation saliency values for lower-level visual characteristics in CVI participants.
  • Predicted significant correlations between fixation saliency values and CVI Range-CR scores.

Conclusions:

  • AI-enabled saliency analysis with eye tracking offers an objective measure for quantifying visual processing abnormalities in pediatric CVI.
  • This innovative technique holds promise for tailoring individualized interventions for children with CVI.
  • The method can potentially serve as a standardized outcome measure in future clinical trials for pediatric visual impairment.