Related Experiment Video
Updated: May 29, 2025
05:46
Introduction of Intracapsular Rotary-cut Procedures IRCP: A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
9.7K
Uterine Rupture During Induced Abortion in the Second Trimester
Catarina Silva1, Rita Palma1, Rita Luz1
1Department of Obstetrics and Gynecology, Hospital Garcia de Orta, Almada, PRT.
Cureus
|February 3, 2025
Summary
Second-trimester termination of pregnancy (TOP) is safe with medical options. However, uterine scars increase rupture risk, as seen in a rare case using mifepristone-misoprostol and sulprostone.
Area of Science:
- Reproductive Medicine
- Obstetrics and Gynecology
Background:
- Second-trimester termination of pregnancy (TOP) is performed in less than 10% of abortions.
- Medical TOP is a safe and effective alternative to surgical procedures.
- Prostaglandins are used for cervical ripening but pose a uterine rupture risk with uterine scars.
Observation:
- A rare case of uterine rupture occurred during a second-trimester TOP at 20 weeks.
- The patient had a history of cesarean delivery.
- The TOP regimen included mifepristone-misoprostol and sulprostone.
Findings:
- Medical TOP in the second trimester, particularly with uterine scars, carries a risk of uterine rupture.
- The combination of mifepristone-misoprostol and sulprostone was used in this case.
Implications:
- Increased cesarean delivery rates necessitate awareness of TOP risks in women with uterine scars.
- This case highlights the importance of careful patient selection and monitoring for medical TOP in women with prior uterine surgery.
- Further research may be needed to refine safety protocols for medical TOP in high-risk populations.
Related Concept Videos
01:27Ovarian Cycle
945
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
945
01:07Teratogenicity
2.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
01:22Esophageal Perforation-I: Introduction
58
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
58