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Stimulus-responsive smart bioactive glass composites for repair of complex tissue defects
Yulian Yang1, Yonghao Qiu1, Cai Lin2
1Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou 510280, PR China.
Theranostics
|February 3, 2025
Summary
Smart bioactive glass composites (SBGC) offer active environmental responsiveness for tissue regeneration. These smart materials actively treat tissue defects by responding to internal or external stimuli, advancing bioactive glass research.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Materials Chemistry
Background:
- Bioactive glasses (BG) are traditionally studied for bioactivity.
- The smart, responsive properties of BG have been largely unexplored.
- Environmental responsiveness is a key feature of modern biomaterials.
Purpose of the Study:
- To introduce the concept of Smart Bioactive Glass Composites (SBGC).
- To review the response characteristics of SBGC to various stimuli.
- To explore SBGC applications in complex tissue defect repair.
Main Methods:
- Literature review of smart biomaterials and bioactive glasses.
- Analysis of SBGC responsiveness to endogenous and exogenous stimuli.
- Examination of SBGC applications in tumor, infection, and diabetes-related tissue defects.
Main Results:
- SBGC actively respond to disease microenvironments and physical stimuli.
- SBGC demonstrate potential in treating complex tissue defects.
- The review synthesizes current progress in SBGC research.
Conclusions:
- SBGC represent a novel class of smart biomaterials.
- SBGC offer advanced therapeutic strategies for tissue regeneration.
- Future research directions for next-generation BG are identified.
