Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatial Clustering and Multivariate Typologies During Lifespan of Hospitalized Traumatic Brain Injury Cases: A Population-Based Study.

American journal of public health·2026
Same author

Transcranial Temporal Interference Stimulation: A Brief Review of Architectures, Circuits, and Application Challenges.

IEEE open journal of engineering in medicine and biology·2026
Same author

Real-time reinforcement for human-machine interface control.

Neuron·2026
Same author

Temporal interference stimulation for deep brain neuromodulation in humans.

Nature biomedical engineering·2026
Same author

Reply: Blinding integrity in cross-frequency transcranial alternating current stimulation for hemianopia.

Brain : a journal of neurology·2026
Same author

Regular outdoor access decreases stress with positive effects on the health of growing pigs raised on a conventional farm.

Scientific reports·2026
Same journal

Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.

Brain : a journal of neurology·2026
Same journal

Time to reconsider risk for psychosis?

Brain : a journal of neurology·2026
Same journal

A descending posterior insular pathway drives sensory hypersensitivity in neuropathic pain.

Brain : a journal of neurology·2026
Same journal

GIT1 loss of function causes a recognizable syndromic neurodevelopmental disorder.

Brain : a journal of neurology·2026
Same journal

RBMX functional retrocopy safeguards brain development in a species-dependent context.

Brain : a journal of neurology·2026
Same journal

Multiple spinal muscular atrophy disease-modifying effects of a Hspa8G470R synaptic chaperone variant.

Brain : a journal of neurology·2026
See all related articles

Related Experiment Video

Updated: May 29, 2025

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

1.1K

Pathway-dependent brain stimulation responses indicate motion processing integrity after stroke.

Michele Bevilacqua1,2, Fabienne Windel1,2, Elena Beanato1,2

  • 1Defitech Chair of Clinical Neuroengineering, Neuro-X Institute (INX), École Polytechnique Fédérale de Lausanne (EPFL), Geneva 1202, Switzerland.

Brain : a Journal of Neurology
|February 4, 2025
PubMed
Summary
This summary is machine-generated.

Cortico-cortical paired associative stimulation (ccPAS) improved motion discrimination in the blind field of stroke survivors with homonymous hemianopia (HH). This targeted brain stimulation enhanced residual visual pathways, offering potential for recovery strategies.

Keywords:
Granger Causalitycortico-cortical paired associative stimulation (ccPAS)direction discriminationhemianopiatranscranial magnetic stimulation-electroencephalography (TMS-EEG)

More Related Videos

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.1K
Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

11.4K

Related Experiment Videos

Last Updated: May 29, 2025

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

1.1K
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

9.1K
Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

11.4K

Area of Science:

  • Neuroscience
  • Neurorehabilitation
  • Visual Neuroscience

Background:

  • Homonymous hemianopia (HH) is a common visual impairment after stroke, impacting survivors' quality of life.
  • Existing treatments focus on perceptual training to enhance residual visual pathways.
  • Understanding plasticity mechanisms in the visual cortex is crucial for developing effective interventions.

Purpose of the Study:

  • To investigate the efficacy of cortico-cortical paired associative stimulation (ccPAS) in inducing plasticity within the V1-MT pathway.
  • To assess the impact of bidirectional ccPAS on visual motion discrimination in stroke patients with HH.
  • To explore electrophysiological and structural correlates of ccPAS response.

Main Methods:

  • A double-blind, crossover study involving 16 stroke patients with HH.
  • Application of bidirectional ccPAS (V1-to-MT and MT-to-V1) targeting the motion processing pathway.
  • Assessment of motion discrimination, EEG-Granger Causality, and structural integrity (V1-MT).

Main Results:

  • MT-to-V1 ccPAS significantly enhanced motion direction discrimination in the blind field.
  • Electrophysiological evidence of increased top-down MT-to-V1 input was observed only in patients who improved.
  • Responders showed enhanced functional coupling within the visual network and preserved V1-MT structural integrity.

Conclusions:

  • Targeted ccPAS can effectively modulate residual visual pathways in stroke patients.
  • The findings suggest ccPAS as a potential therapeutic tool for visual recovery in HH.
  • Patient stratification based on functional and structural markers may optimize ccPAS efficacy.