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Updated: May 29, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

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Published on: September 7, 2022

Erythema Multiforme Secondary to Mumps.

LakshmiPrasad Lakshmipathi¹, Yogindher Singh¹, Manobalan Karunanandhan¹

¹Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, India.

The American Journal of Tropical Medicine and Hygiene

|February 4, 2025

Summary

Erythema multiforme (EMF) is an immune-mediated condition. This case report highlights mumps as a rare trigger for EMF, emphasizing the need to consider uncommon viral infections.

Area of Science:

Dermatology
Infectious Diseases
Immunology

Background:

Erythema multiforme (EMF) is an immune-mediated skin condition with diverse triggers.
Infections and drug reactions are the most common causes of EMF.
Identifying specific etiologies is crucial for patient management.

Observation:

A case of erythema multiforme (EMF) is presented in a 22-year-old male.
The patient exhibited characteristic targetoid lesions on the skin and mucosa.
Symptoms preceded by fever and parotid enlargement, suggestive of mumps.

Findings:

Serological tests confirmed elevated IgM antibody titers to mumps.
This indicates a causal link between mumps infection and the development of EMF.

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Mumps is identified as a rare but potential etiology for erythema multiforme.

Implications:

This case expands the known spectrum of erythema multiforme (EMF) triggers.
Highlights the importance of considering uncommon viral infections, such as mumps, in EMF diagnosis.
Suggests that a broader range of infectious agents should be investigated in patients with unexplained EMF.