Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adhesion01:14

Adhesion

39.7K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
39.7K
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

2.5K
In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
2.5K
Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

2.6K
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
2.6K
Anchoring Junctions01:03

Anchoring Junctions

3.6K
Anchoring junctions are multiprotein complexes that help cells connect to other cells and the extracellular matrix. Anchoring junctions are present on the lateral and basal surfaces of cells, providing strong and flexible connections. Focal adhesions are often formed due to cell interactions with the ECM substrata, which initiate signal transduction via kinase cascades and other mechanisms. Together, they provide stability and tissue integrity. There are three types of anchoring junctions:...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interface Engineering and Strain Distribution in Microcracked MXene/Carbon Nanofiber-Based Strain Sensors.

ACS sensors·2026
Same author

Hydroxyl-rich nanocavities on perovskite enable nearly barrierless intramolecular hydrogen transfer for nitrate electroreduction to ammonia.

Nature communications·2026
Same author

Chirality-Induced Spin-Selective Transduction of Circularly Polarized Light for Polarization-Neurochemical Coupling.

ACS nano·2026
Same author

Lung cancer associated with cystic airspaces in the perioperative immunotherapy era: radiologic and pathologic pitfalls, surgical extent, and management implications.

Translational lung cancer research·2026
Same author

How Slippery Surfaces Retain Their Function: Lubricant Film Dynamics Upon Droplet Contact.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Corrigendum to 'Functional nucleic acid hydrogels: Paving the way for next-generation bone and cartilage regeneration' [Mater. Today Bio 2025, 423, 102708].

Materials today. Bio·2026

Related Experiment Video

Updated: May 29, 2025

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid
08:58

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid

Published on: December 2, 2022

2.9K

Stiffer Is Stickier: Adhesion in Elastic Nanofilms.

Chuanli Yu1, Weijia Zeng1, Bingjie Wang2

  • 1Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complex Systems, College of Engineering, Peking University, Beijing 100871, China.

Nano Letters
|February 5, 2025
PubMed
Summary

Researchers found that tensioning elastic graphene films makes them stiffer and stickier. This "stiffer-stickier" phenomenon, explained by a new multiscale theory, is crucial for understanding adhesion in thin film materials.

Keywords:
AdhesionDelaminationDetachment forceGrapheneThin films

More Related Videos

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
08:02

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

10.6K
Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
12:26

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Published on: January 29, 2022

5.5K

Related Experiment Videos

Last Updated: May 29, 2025

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid
08:58

Atomic Force Microscopy Cantilever-Based Nanoindentation: Mechanical Property Measurements at the Nanoscale in Air and Fluid

Published on: December 2, 2022

2.9K
Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
08:02

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization

Published on: July 3, 2018

10.6K
Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
12:26

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Published on: January 29, 2022

5.5K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Physics

Background:

  • Adhesion is critical in nature and engineering, particularly for thin film materials.
  • Understanding the detachment force is complex due to nonlinear deformation and adhesion interactions.
  • Existing macroscopic adhesion theories do not fully explain observed phenomena in nanoscale systems.

Purpose of the Study:

  • To quantitatively investigate the detachment force between a sphere and an elastic graphene film.
  • To develop a formal theory explaining adhesion behavior in this canonical configuration.
  • To explore the effect of film tension on adhesion and stiffness.

Main Methods:

  • Controlled experimental separation of a sphere from an elastic graphene film.
  • Development of formal theories to model the detachment force.
  • Analysis of the relationship between film tension, stiffness, and adhesion.

Main Results:

  • Observed that applying tension to the graphene film increases its apparent stiffness and detachment force.
  • Identified this behavior as "stiffer-stickier", contradicting macroscopic adhesion theories.
  • Demonstrated this is a general phenomenon for elastic nanofilms.

Conclusions:

  • The "stiffer-stickier" behavior is attributed to long-range intermolecular forces.
  • A novel multiscale theory explains the observed adhesion phenomena.
  • The findings provide a generic strategy for understanding the adhesion of slender structures across scales.