Chirality-Induced Spin-Selective Transduction of Circularly Polarized Light for Polarization-Neurochemical Coupling

Circularly polarized light (CPL) provides a powerful optical degree of freedom for information encoding, yet most CPL-responsive systems rely on weak circular dichroism-based absorption and lack chemically amplified readout mechanisms. Here, we report a chirality-driven spin-photonic transduction platform in which CPL helicity is converted into polarization-dependent interfacial redox modulation within a chirality-induced spin selectivity (CISS)-consistent framework. A chiral plasmonic Au/Vo-CeO₂ gate exhibits helicity-dependent hot-carrier dynamics and interfacial charge transfer, consistent with plasmonic spin orbit coupling related processes and CISS-related interfacial transport. The resulting helicity-dependent photovoltage response induces amplified electrochemical modulation of a PEDOT:PSS channel in an aqueous transistor. Meanwhile, dopamine oxidation at the chiral gate provides chemical amplification that strengthens polarization-dependent responses. The resulting system enables CPL discrimination in electrolyte and demonstrates polarization-controlled chemical transduction. As functional validation, the CPL-dopamine coupling enhances signal differentiation in pattern-recognition tasks and enables chemically gated, polarization-guided wing actuation, forming a compact perception-action loop. These results demonstrate a CISS-consistent spin-related interfacial transduction strategy for CPL detection and chemical signal amplification in chiral optoelectronic and spin-related interfacial systems.